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Maduramicin ammonium which is included  in coccidiostat, effects extracellular agamic forms of coccidiums; and resistant forms to other ionophoric antibiotic.

The mechanism of preparation action is in elective damage of sodium and potassium ion transport through  culprit cell membrane which leads to its death.

Preparation is output from organism in the form of metabolites mostly with excrement. Maduramicin ammonium together with well-known antibiotics, vitamins and other feed additives are used in poultry excluding  tiamulin.

Maduramicin ammonium (1 %) should be given to broilers from the first day of life, but it is output when 5 days before killing. Preparation is given in the mash with feeding in the doze of 0,5 кg for 1 t of feeding, that’s it  - 0,005 g maduramicin ammonium for 1 кg of feeding. To ensure a uniform distribution of the daily dose maduramicin ammonium 1% is mixed with a small amount of feed, and then make at careful hashing in food, calculated on the consumption of poultry during the day.



Salinomycin is poly antibiotic of ionophores goup. It provides antococcid action to all types of coccidiosis originator. It shows activity to gram-positive microorganisms, some anaerobic micronychia and Serpulina (Treponema) hyodysenteria. Biological activity is based on its ability to make complexes with ions of monovalent alcali metals, that’s leads to the damage of their transport through cells coccidium interseptum. Thus, intracellular concentration of ions in culprit cells is damaged. The action is occurred in the earliest stage of coccidium development. Adding of salinomycin in particular dozes to the feedings for animals with developed proventriculus causes growth enlarging and feeding   uptaking. Salinomycin effects microbiology and microfauna in proventriculus, as a result concentration of propionic acid increases and mass of methane decreases.

Salinomycin sodium is used for the prevention of coccidiosis of chickens caused by Eimeria tenella, E.acervulina, E.mivati, E.maxima, E.necatrix; to increase growth and reduce feed for fattening of pigs, lambs and calves.



Monensin sodium in the composition of coccidiostatic is active to all types of coccidiums  parasitizing (E.tenella, E.necatrix, E.mivati, E.maxima, E.brunetty, E.mitis, E.praecox.). Preparation action mechanism is based on the damage of transport of cation sodium and kalium in oocyst, which leads to the coccidiums death on the stage of schizogony. While peroral input monensin sodium isn’t absorbed in the digestive tract and influences mucus and submucous membranes. It is output in the original form with excrements in 3 days. Monensin sodium is used for coccidiosis prophylaxis of broilers and rearing stock.

Monensin sodium (10 %) is used to a bird in a mix with feed in the following dozes: broilers - 1000 - 1250 g per 1 ton of feed (100 - 125 g of monensin sodium DV) from the first day of life and is excluded from the diet for 5 days before slaughter. Repair young growth of hens - 1000 - 1200 g (100 - 120 g of monensin sodium DV) from the first days of life up to 16 weeks of age. To ensure even distribution, the daily dose of monensin sodium is mixed with a small amount of feed, and then is added at careful hashing in food, calculated on the consumption of poultry during the day.

It mustn’t be given together with tiamulin, erythromycin, oleandomycin and sulfanilamides. It mustn’t be given to laying hen, mature breeding bird and other sorts of stock. 


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